SNCA variants rs2736990 and rs356220 as risk factors for Parkinson's disease but not for amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population.

doi:10.1016/j.neurobiolaging.2014.07.014

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SNCA variants rs2736990 and rs356220 as risk factors for Parkinson's disease but not for amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population.

Neurobiology of aging - 1 Dec 2014

Guo Xiao Yan, Chen Yong Ping, Song Wei, Zhao Bi, Cao Bei, Wei Qian Qian, Ou Ru Wei, Yang Yuan, Yuan Li Xing, Shang Hui-Fang

Abstract excerpt

Previous studies found that polymorphisms rs2736990 and rs356220 in the alpha-synuclein (SNCA) gene increase the risk for Parkinson's disease (PD) in a Caucasian population. In consideration of the overlapping of clinical manifestations and pathologic characteristics among PD, amyotrophic lateral sclerosis (ALS), and multiple system atrophy (MSA), the possible associations of these 2 polymorphisms and 3...

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alpha-Synuclein
Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Asian People

Genetic Association Studies

Multiple System Atrophy

Parkinson Disease

Polymorphism, Genetic

Risk Factors

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PMID: 25129240
DOI: 10.1016/j.neurobiolaging.2014.07.014

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SNCA

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