Article
Mitochondrial DNA haplogroup D4b is a protective factor for ischemic stroke in Chinese Han population.
Molecular genetics and genomics : MGG - 1 Dec 2014
Yang Dongzhi, Wang Qing, Shi Yunshu, Fan Yujia, Zheng Hong-Xiang, Song Guoying, Feng Qingchuan, Zheng Hong, He Ying
Abstract excerpt
Mitochondrial DNA (mtDNA) haplogroups affect the assembly and stability of the mitochondrial respiratory chain, which is potentially related to susceptibility to ischemic stroke (IS). However, the role of mtDNA in IS has not been comprehensively studied. The purpose of this study was to explore whether mtDNA polymorphisms and haplogroups are involved in the etiology of IS in the Chinese Han population. We...
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