Article
Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population.
Journal of the American Heart Association - 4 Oct 2022
Shi Mengyao, Kelly Tanika N, Zhu Zhengbao, Li Changwei, Shen Chong, Sun Yingxian, Wang Aili, Shan Guangliang, Bu Xiaoqing, Guo Daoxia, Zhao Jingbo, Xu Tan, Peng Hao, Xu Tian, Zhong Chongke, Sun Xiao, Chen Jing, Zhang Yonghong, He Jiang
Abstract excerpt
Background Ischemic stroke is likely caused by interactions of multiple genes and environmental determinants. However, large-scale sequencing studies to discern functional genetic variants and their interactions with clinical and lifestyle risk factors on ischemic stroke are limited. Methods and Results We sequenced functional regions of 740 previously identified genes associated with atherosclerotic disease...
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