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Article

Mitochondrial haplogroups H and J: risk and protective factors for ischemic cardiomyopathy.

PloS one - 1 Jan 2012

Fernández-Caggiano Mariana, Barallobre-Barreiro Javier, Rego-Pérez Ignacio, Crespo-Leiro María G, Paniagua María Jesus, Grillé Zulaika, Blanco Francisco J, Doménech Nieves

Abstract excerpt

BACKGROUND: Since mitochondria are the principal source of reactive oxygen species (ROS), these organelles may play an important role in ischemic cardiomyopathy (IC) development. The mitochondrial genome may influence this disease. The aim of the present study was to test the relationship between IC development and the impact of single nucleotide polymorphisms (SNPs) in mitochondrial DNA (mtDNA) defining the...

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Identifiers

PMID: 22937160
DOI: 10.1371/journal.pone.0044128
PMCID: PMC3429437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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