Article
Mitochondrial haplogroup N9b is protective against myocardial infarction in Japanese males.
Human genetics - 1 Feb 2007
Nishigaki Yutaka, Yamada Yoshiji, Fuku Noriyuki, Matsuo Hitoshi, Segawa Tomonori, Watanabe Sachiro, Kato Kimihiko, Yokoi Kiyoshi, Yamaguchi Sachiyo, Nozawa Yoshinori, Tanaka Masashi
Abstract excerpt
Superoxide, which mitochondria mainly produce in vascular endothelial cells, plays an important role in the pathogenesis of atherosclerosis and coronary artery disease. Accordingly, mitochondrial functional differences are thought to be one of the most important factors for the risk of myocardial infarction among various individuals. In the present study, we surveyed mitochondrial haplogroups associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
