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Integrated Metabolic and Gene Expression Profiling Reveals New Therapeutic Modalities for Rapidly Proliferating Breast Cancers

2021-08-06

Abstract excerpt

<title>Abstract</title> <p>Metabolic dysregulation, although a prominent feature in breast cancer, remains undercharacterized in patient tumors. By performing untargeted metabolomics analyses on triple-negative breast cancer (TNBC) and Estrogen Receptor (ER) positive patient breast tumors, as well as TNBC patient-derived xenografts (PDXs), we identified two major metabolic groups independent of breast cancer hist...

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Literature Corpus work
a538991e-3875-5614-a77f-903ca1d03075
DOI
10.21203/rs.3.rs-117384/v2
Open publication

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Integrated Metabolic and Gene Expression Profiling Reveals New Therapeutic Modalities for Rapidly Proliferating Breast CancersDOI 10.21203/rs.3.rs-117384/v2
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