Article
The Axin2 rs2240308 polymorphism and susceptibility to lung cancer in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2014
Liu Dan, Li Ling, Yang Yuguang, Liu Wentao, Wu Jin
Abstract excerpt
Axis inhibition protein 2 (Axin2) is a negative regulator of the canonical Wnt/β-catenin signaling pathway, and functions as a tumor suppressor in a number of human cancers. Previous pilot studies have suggested an association between Axin2 exon1 148 (rs2240308) SNP polymorphism and risk for lung cancer. In the present study, we aimed to investigate the Axin2 exon1 148 polymorphism and its association with lung...
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