Article
Genotypes and Haplotypes in the AXIN2 and TCF7L2 Genes are Associated With Susceptibility and With Clinicopathological Characteristics in Breast Cancer Patients.
British journal of biomedical science - 1 Jan 2022
Rosales-Reynoso M A, Rosas-Enríquez V, Saucedo-Sariñana A M, Pérez-Coria M, Gallegos-Arreola M P, Salas-González E, Barros-Núñez P, Juárez-Vázquez C I, Flores-Martínez S E, Sánchez-Corona J
Abstract excerpt
Background: Breast cancer is a multifactorial disease whose genetic susceptibility is related to polymorphic variants of cell proliferation and migration pathways. Variants in AXIN2 and TCF7L2 in the Wnt-β catenin pathway have been associated with different types of cancer; however, little is known about its role in breast cancer. This study tests the hypothesis of links between AXIN2 rs1133683 and rs2240308, and...
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