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Article

Single nucleotide polymorphism of the AXIN2 gene is preferentially associated with human lung cancer risk in a Japanese population.

International journal of molecular medicine - 1 Aug 2006

Kanzaki Hirotaka, Ouchida Mamoru, Hanafusa Hiroko, Yano Masaaki, Suzuki Hiromitsu, Aoe Motoi, Imai Kazue, Shimizu Nobuyoshi, Nakachi Kei, Shimizu Kenji

Abstract excerpt

The AXIN2 gene, a negative regulator gene of Wnt/beta-catenin signaling, is a putative tumor suppressor gene on human chromosome 17q24. In the genomic locus on which the AXIN2 gene is located, allelic loss and rearrangement were frequently detected in many cancers. An association between human cancer risk and a single nucleotide polymorphism (SNP) at codon 50 of the AXIN2 gene, encoding either proline (CCT) or...

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Identifiers

PMID: 16820935

Genes

AXIN2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Single nucleotide polymorphism of the AXIN2 gene is preferentially associated with human lung cancer risk in a Japanese population.PMID 16820935Read ↗

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