Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NPSR1 polymorphisms influence recurrent abdominal pain in children: a population-based study.

Neurogastroenterology and motility - 1 Oct 2014

Henström M, Zucchelli M, Söderhäll C, Bergström A, Kere J, Melén E, Olén O, D'Amato M

Abstract excerpt

BACKGROUND: Recurrent abdominal pain (RAP) occurs frequently among children and is one of the cardinal symptoms of functional gastrointestinal disorders (FGID). The mechanisms of visceral pain and RAP are not fully understood. A heritable component has been demonstrated and a few candidate genes proposed. NPSR1 encodes the receptor for neuropeptide S (NPS) and NPS-NPSR1 signaling is involved in anxiety,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abdominal Pain
Share to Child
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, G-Protein-Coupled

Share to Recurrence

Share to Sweden

Source

Identifiers

PMID: 25091462
DOI: 10.1111/nmo.12401

Genes

NPSR1
NPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NPSR1 polymorphisms influence recurrent abdominal pain in children: a population-based study.PMID 25091462Read ↗

Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders.Semantic proximity Read ↗

Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).Semantic proximity Read ↗

Neuropeptide s receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Interaction of NPSR1 genotypes and probiotics in the manifestation of atopic eczema in early childhood.Semantic proximity Read ↗

An exploratory machine learning study on paediatric abdominal pain phenotyping and predictionSemantic proximity Read ↗

Analysis of neuropeptide S receptor gene (NPSR1) polymorphism in rheumatoid arthritis.Semantic proximity Read ↗

Homozygosity for the SCN10A Polymorphism rs6795970 Is Associated With Hypoalgesic Inflammatory Bowel Disease PhenotypeSemantic proximity Read ↗

Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management.Semantic proximity Read ↗

Neuropeptide S (NPS) variants modify the signaling and risk effects of NPS Receptor 1 (NPSR1) variants in asthma.Semantic proximity Read ↗

Predictors of health care utilization in young children with recurrent pain – a population-based studySemantic proximity Read ↗

Neandertal introgression and accumulation of hypomorphic mutations in the neuropeptide S (NPS) system promote attenuated functionality.Semantic proximity Read ↗

Identification of Arginine-Vasopressin Receptor 1a (Avpr1a/Avpr1a) as a Novel Candidate Gene for Chronic Visceral Pain Sheds Light on the Potential Role of Enteric Neurons in the Development of Visceral Hypersensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.