Article
Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management.
BMC gastroenterology - 5 Feb 2021
Ledergerber Martina, Lang Brian M, Heinrich Henriette, Biedermann Luc, Begré Stefan, Zeitz Jonas, Krupka Niklas, Rickenbacher Andreas, Turina Matthias, Greuter Thomas, Schreiner Philipp, Roth René, Siebenhüner Alexander, Vavricka Stephan R, Rogler Gerhard, Beerenwinkel Niko, Misselwitz Benjamin
Abstract excerpt
BACKGROUND: Abdominal pain is a frequent symptom in patients with inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC). Pain can result from ongoing inflammation or functional disorders imitating irritable bowel syndrome (IBS). Several single-nucleotide polymorphisms (SNPs) have been associated with IBS. However, the impact of IBS genetics on the clinical course of IBD,...
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