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Article

Wide-Ranging Effects of the Yeast Ptc1 Protein Phosphatase Acting Through the MAPK Kinase Mkk1.

Genetics - 1 Jan 2016

Tatjer Laura, Sacristán-Reviriego Almudena, Casado Carlos, González Asier, Rodríguez-Porrata Boris, Palacios Lorena, Canadell David, Serra-Cardona Albert, Martín Humberto, Molina María, Ariño Joaquín

Abstract excerpt

The Saccharomyces cerevisiae type 2C protein phosphatase Ptc1 is required for a wide variety of cellular functions, although only a few cellular targets have been identified. A genetic screen in search of mutations in protein kinase-encoding genes able to suppress multiple phenotypic traits caused by the ptc1 deletion yielded a single gene, MKK1, coding for a MAPK kinase (MAPKK) known to activate the cell-wall...

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Identifiers

PMID: 26546002
DOI: 10.1534/genetics.115.183202
PMCID: PMC4701081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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