Article
Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae.
Genetics - 1 Apr 2002
Williams-Hart Tara, Wu Xiaolin, Tatchell Kelly
Abstract excerpt
Protein phosphatase type 1 (PP1) is encoded by the essential gene GLC7 in Saccharomyces cerevisiae. glc7-109 (K259A, R260A) has a dominant, hyperglycogen defect and a recessive, ion and drug sensitivity. Surprisingly, the hyperglycogen phenotype is partially retained in null mutants of GAC1, GIP2, and PIG1, which encode potential glycogen-targeting subunits of Glc7. The R260A substitution in GLC7 is responsible...
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