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Article

SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex.

Neuron - 20 Aug 2014

Insolera Ryan, Shao Wei, Airik Rannar, Hildebrandt Friedhelm, Shi Song-Hai

Abstract excerpt

Mutations of SDCCAG8 are associated with nephronophthisis and Bardet-Biedl syndrome, as well as schizophrenia; however, the function of SDCCAG8 remains largely unknown. Here, we show that SDCCAG8 regulates centrosomal accumulation of pericentriolar material and neuronal polarization and migration in the developing mouse cortex. Sdccag8 expression is selectively elevated in newborn neurons prior to their...

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Source

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Identifiers

PMID: 25088364
DOI: 10.1016/j.neuron.2014.06.029
PMCID: PMC4141904

Genes

SDCCAG8
PCM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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