Article
HLA-C -35kb expression SNP is associated with differential control of β-HPV infection in squamous cell carcinoma cases and controls.
PloS one - 1 Jan 2014
Vineretsky Karin A, Karagas Margaret R, Kuriger-Laber Jacquelyn K, Waterboer Tim, Pawlita Michael, Nelson Heather H
Abstract excerpt
A single nucleotide polymorphism (SNP) 35 kb upstream of the HLA-C gene is associated with HLA-C expression, and the high expressing genotype (CC) has been associated with HIV-I control. HLA-C is unique among the classical MHC class I molecules for its role in the control of viral infections and recognition of abnormal or missing self. This immunosurveillance is central to the pathogenesis of non-melanoma skin...
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