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Article

Next-generation sequencing reveals large connected networks of intra-host HCV variants.

BMC genomics - 1 Jan 2014

Campo David S, Dimitrova Zoya, Yamasaki Lilian, Skums Pavel, Lau Daryl Ty, Vaughan Gilberto, Forbi Joseph C, Teo Chong-Gee, Khudyakov Yury

Abstract excerpt

BACKGROUND: Next-generation sequencing (NGS) allows for sampling numerous viral variants from infected patients. This provides a novel opportunity to represent and study the mutational landscape of Hepatitis C Virus (HCV) within a single host. RESULTS: Intra-host variants of the HCV E1/E2 region were extensively sampled from 58 chronically infected patients. After NGS error correction, the average number of reads...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Viral

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Source

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Identifiers

PMID: 25081811
DOI: 10.1186/1471-2164-15-S5-S4
PMCID: PMC4120142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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