Article
Transmission Networks of HCV Genotype 1a Enriched With Pre-existing Polymorphism Q80K Among HIV-Infected Patients With Acute Hepatitis C in Poland.
Journal of acquired immune deficiency syndromes (1999) - 15 Apr 2018
Parczewski Miłosz, Cielniak Iwona, Kordek Justyna, Aksak-Wąs Bogusz, Urbańska Anna, Leszczyszyn-Pynka Magdalena, Siwak Ewa, Bociąga-Jasik Monika, Nowak Anna, Szymczak Aleksandra, Zalewska Małgorzata, Łojewski Władysław, Vandamme Anne-Mieke, Lübke Nadine, Cuypers Lize
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) resistance-associated variants (RAVs) have been shown to adversely affect treatment response of direct-acting antivirals. Identifying pre-existing RAVs and transmission networks among HIV/HCV genotype 1 (G1)-infected patients from Poland will assist in shaping surveillance strategies for HCV. METHODS: NS3 and NS5A sequences were obtained from samples of 112 direct-acting...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
