Article

Receptor for Hyaluronan-Mediated Motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients

2022-06-17

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer invasion and metastasis result from a complex interplay between tumor cells and the tumor microenvironment (TME). Key oncogenic changes in the TME include aberrant metabolism and subsequent signaling of hyaluronan (HA). Hyaluronan Mediated Motility Receptor (RHAMM, HMMR ) is a HA receptor that enables tumor cells to sense and respond to the TME during breast cancer progression. Fo...

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Literature Corpus work: 08ac8f25-52d2-5383-8bac-ffa69df824aa
DOI: 10.1101/2022.06.13.495375

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