Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The associations of polymorphisms of TSH receptor and thyroid hormone receptor genes with L-thyroxine treatment in hypothyroid patients.

Hormones (Athens, Greece) - 1 Jan 2000

Al-Azzam Sayer I, Alzoubi Karem H, Khabour Omar, Al-Azzeh Ola

Abstract excerpt

OBJECTIVE: To investigate the possible association between response to levothyroxine (L-T4) doses in hypothyroid patients and variation in thyroid stimulating hormone receptor (TSHR) gene and thyroid hormone receptor (THRα) gene. DESIGN: This cross-sectional correlation study included 228 patients with primary hypothyroidism who were using L-T4 replacement therapy. Thyroid function test was performed using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormone Replacement Therapy
Share to Hypothyroidism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Obesity, Abdominal

Share to Receptors, Thyrotropin

Share to Thyroid Function Tests

Share to Thyroid Hormone Receptors alpha

Share to Thyroxine

Share to Waist Circumference

Source

Identifiers

PMID: 25079464
DOI: 10.14310/horm.2002.1488

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The associations of polymorphisms of TSH receptor and thyroid hormone receptor genes with L-thyroxine treatment in hypothyroid patients.PMID 25079464Read ↗

Treatment of hypothyroidism with levothyroxine plus slow-release liothyronine; A Study Protocol for a Randomized Controlled Double-Blinded Clinical TrialSemantic proximity Read ↗

Association of TSHR gene single nucleotide intronic polymorphism with the risk of hypothyroid and hyperthyroid disorders in Yazd province.Semantic proximity Read ↗

Subclinical hypothyroidism in children and adolescents: a wide range of clinical, biochemical, and genetic factors involved.Semantic proximity Read ↗

The role of type II deiodinase polymorphisms in clinical management of hypothyroid patients treated with levothyroxine.Semantic proximity Read ↗

The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations.Semantic proximity Read ↗

Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients.Semantic proximity Read ↗

Identification and consequences of polymorphisms in the thyroid hormone receptor alpha and beta genes.Semantic proximity Read ↗

TSHR rs2288496 associated with thyroid hormone and predict the occurrence of lymph node metastasis of papillary thyroid cancer.Semantic proximity Read ↗

Thyroid Function Characteristics and Determinants: The Rotterdam Study.Semantic proximity Read ↗

SNP rs11185644 in RXRA gene and SNP rs2235544 in DIO1 gene predict dosage requirements in a cross-sectional sample of hypothyroid patients.Semantic proximity Read ↗

Associationj of TSHR Gene Single Neucleotide Intronic Polymorphism with the Risk of Hypothyroid and Hyperthyroid Disorders in Yazd Province.Semantic proximity Read ↗

Burden, risk factors and outcomes associated with adequately treated hypothyroidism in a population-based cohort of pregnant women from North IndiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.