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Article

Subclinical hypothyroidism in children and adolescents: a wide range of clinical, biochemical, and genetic factors involved.

The Journal of clinical endocrinology and metabolism - 1 Jul 2009

Rapa Anna, Monzani Alice, Moia Stefania, Vivenza Daniela, Bellone Simonetta, Petri Antonella, Teofoli Francesca, Cassio Alessandra, Cesaretti Graziano, Corrias Andrea, de Sanctis Vincenzo, Di Maio Salvatore, Volta Cecilia, Wasniewska Malgorzata, Tatò Luciano, Bona Gianni

Abstract excerpt

OBJECTIVE: The aim of the study was to examine clinical characteristics, biochemical parameters, and TSH-R gene variations in children and adolescents with subclinical hypothyroidism (SH) in order to evaluate their pattern of distribution in SH. PATIENTS: We enrolled 88 patients, each having at least two TSH measurements above the upper limit of the reference range with normal free thyroid hormones and negative...

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PMID: 19417038
DOI: 10.1210/jc.2009-0375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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