Article
Network-based analysis of genotype-phenotype correlations between different inheritance modes.
Bioinformatics (Oxford, England) - 15 Nov 2014
Hao Dapeng, Li Chuanxing, Zhang Shaojun, Lu Jianping, Jiang Yongshuai, Wang Shiyuan, Zhou Meng
Abstract excerpt
MOTIVATION: Recent studies on human disease have revealed that aberrant interaction between proteins probably underlies a substantial number of human genetic diseases. This suggests a need to investigate disease inheritance mode using interaction, and based on which to refresh our conceptual understanding of a series of properties regarding inheritance mode of human disease. RESULTS: We observed a strong...
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