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Article

Systematic large-scale study of the inheritance mode of Mendelian disorders provides new insight into human diseasome.

European journal of human genetics : EJHG - 1 Nov 2014

Hao Dapeng, Wang Guangyu, Yin Zuojing, Li Chuanxing, Cui Yan, Zhou Meng

Abstract excerpt

One important piece of information about the human Mendelian disorders is the mode of inheritance. Recent studies of human genetic diseases on a large scale have provided many novel insights into the underlying molecular mechanisms. However, most successful analyses ignored the mode of inheritance of diseases, which severely limits our understanding of human disease mechanisms relating to the mode of inheritance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24448549
DOI: 10.1038/ejhg.2013.309
PMCID: PMC4200425

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