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Article

A systematic characterization of genes underlying both complex and Mendelian diseases.

Human molecular genetics - 1 Apr 2012

Jin Wenfei, Qin Pengfei, Lou Haiyi, Jin Li, Xu Shuhua

Abstract excerpt

Traditionally, genetic disorders have been classified as either Mendelian diseases or complex diseases. This nosology has greatly benefited genetic counseling and the development of gene mapping strategies. However, based on two well-established databases, we identified that 54% (524 of 968) of the Mendelian disease genes were also involved in complex diseases, and this kind of genes has not been systematically...

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PMID: 22186022
DOI: 10.1093/hmg/ddr599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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