Article
CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa).
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020
Olvany Jasmine M, Sausville Lindsay N, White Marquitta J, Tacconelli Alessandra, Tavera Gloria, Sobota Rafal S, Ciccacci Cinzia, Bohlbro Anders S, Wejse Christian, Williams Scott M, Sirugo Giorgio
Abstract excerpt
Tuberculosis (TB) is the leading cause of death from a single infectious agent. According to the WHO, 85% of cases in 2018 were pulmonary tuberculosis (PTB), making it the most prevalent form of the disease. Although the bacillus responsible for disease, Mycobacterium tuberculosis (MTB), is estimated to infect 1.7 billion people worldwide, only a small portion of those infected (5-10%) will transition into active...
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