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Article

Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption.

PloS one - 1 Jan 2014

McMahon George, Taylor Amy E, Davey Smith George, Munafò Marcus R

Abstract excerpt

Two genetic loci, one in the cytochrome P450 1A1 (CYP1A1) and 1A2 (CYP1A2) gene region (rs2472297) and one near the aryl-hydrocarbon receptor (AHR) gene (rs6968865), have been associated with habitual caffeine consumption. We sought to establish whether a more refined and comprehensive assessment of caffeine consumption would provide stronger evidence of association, and whether a combined allelic score...

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Source

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Identifiers

PMID: 25075865
DOI: 10.1371/journal.pone.0103448
PMCID: PMC4116211

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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