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Article

Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic Burkitt lymphoma.

The American journal of tropical medicine and hygiene - 1 Sept 2014

Oduor Cliff I, Chelimo Kiprotich, Ouma Collins, Mulama David H, Foley Joslyn, Vulule John, Bailey Jeffrey A, Moormann Ann M

Abstract excerpt

Overexpression of interleukin-6 (IL-6) and IL-10 in endemic Burkitt lymphoma (eBL) may facilitate tumorigenesis by providing a permissive cytokine milieu. Promoter polymorphisms influence interindividual differences in cytokine production. We hypothesized that children genetically predisposed for elevated cytokine levels may be more susceptible to eBL. Using case-control samples from western Kenya consisting of...

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Share to Burkitt Lymphoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-10

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 25071000
DOI: 10.4269/ajtmh.13-0616
PMCID: PMC4155573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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