Article
Relationship of Epstein-Barr virus and interleukin 10 promoter polymorphisms with the risk and clinical outcome of childhood Burkitt lymphoma.
PloS one - 1 Jan 2012
Minnicelli Carolina, Barros Mário H M, Klumb Claudete E, Romano Sérgio O, Zalcberg Ilana R, Hassan Rocio
Abstract excerpt
Epstein-Barr virus (EBV) is an important environmental factor associated to the development of Burkitt lymphoma (BL) in endemic and intermediate risk regions. However, little is known about the contribution of genetic constitution to the development and clinical response of the disease. The aim of this work was to investigate the role of EBV and Interleukin 10 (IL10) single nucleotide polymorphisms (-1082A/G,...
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