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Article

Association of killer cell immunoglobulin-like receptors with endemic Burkitt lymphoma in Kenyan children.

Scientific reports - 31 May 2021

Muriuki Beatrice M, Forconi Catherine S, Oluoch Peter O, Bailey Jeffrey A, Ghansah Anita, Moormann Ann M, Ong'echa John M

Abstract excerpt

Endemic Burkitt lymphoma (eBL) is an aggressive pediatric B cell lymphoma, common in Equatorial Africa. Co-infections with Epstein-Barr virus (EBV) and Plasmodium falciparum, coupled with c-myc translocation are involved in eBL etiology. Infection-induced immune evasion mechanisms to avoid T cell cytotoxicity may increase the role of Natural killer (NK) cells in anti-tumor immunosurveillance. Killer...

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Share to Burkitt Lymphoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Herpesvirus 4, Human

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Source

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Identifiers

PMID: 34059753
DOI: 10.1038/s41598-021-90596-7
PMCID: PMC8166913

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