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Article

The BDNF Val66Met polymorphism, resting-state hippocampal functional connectivity and cognitive deficits in acute late-onset depression.

Journal of affective disorders - 1 Sept 2015

Yin Yingying, Hou Zhenghua, Wang Xiaoquan, Sui Yuxiu, Yuan Yonggui

Abstract excerpt

OBJECTIVE: To investigate the relationship between hippocampal functional connectivity (HFC), cognitive deficits, and the influence of BDNF Val66Met polymorphism on the HFC in acute late-onset depression (LOD). METHODS: 26 LOD patients and 33 and normal controls (NCs) completed clinical assessments, neuropsychological testing, blood samples collecting for genotyping, and resting-state functional MRI (R-fMRI)...

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Identifiers

PMID: 26000753
DOI: 10.1016/j.jad.2015.04.050

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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