Article
Association analysis of melanocortin 3 receptor polymorphisms with the risk of pulmonary tuberculosis.
Lung - 1 Dec 2014
Park Byung Lae, Kim Lyoung Hyo, Namgoong Suhg, Kim Ji On, Kim Jason Yongha, Chang Hun Soo, Park Jong Sook, Jang An Soo, Park Sung Woo, Kim Do Jin, Kim Ki Up, Kim Yang Gee, Uh Soo-Taek, Seo Ki Hyun, Kim Young Hoon, Park Choon Sik, Shin Hyoung Doo
Abstract excerpt
PURPOSE: Melanocortin 3 Receptor (MC3R) is one of the families of seven-transmembrane G-protein-coupled receptors, and a recent study showed that MCR3 promoter polymorphism was significantly associated with the susceptibility of tuberculosis (TB) in South African population. METHODS: We analyzed six MC3R polymorphisms to examine the genetic effects on the risk of pulmonary TB in Korean subjects by using TaqMan...
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