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Article

Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.

European journal of human genetics : EJHG - 1 Jun 2011

Adams Lindsey A, Möller Marlo, Nebel Almut, Schreiber Stefan, van der Merwe Lize, van Helden Paul D, Hoal Eileen G

Abstract excerpt

We have validated the association of two genes on chromosome 20q13.31-33 with tuberculosis susceptibility. A previous genome-wide linkage study performed by Cooke et al identified the genes melanocortin-3-receptor (MC3R) and cathepsin Z (CTSZ) as possible candidates in tuberculosis susceptibility. MC3R has been implicated in obesity studies and is known to play a role in many biological systems including the...

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Identifiers

PMID: 21368909
DOI: 10.1038/ejhg.2011.1
PMCID: PMC3110050

Genes

CTSZ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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