Article
rs6127698 polymorphism in the MC3R gene and susceptibility to multifocal tuberculosis in southern Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2020
Xu Peng, Gao Qi-le, Wang Yun-Jia, Guo Chao-Feng, Tang Ming-Xing, Liu Shao-Hua, Deng Ang, Wang Yu-Xiang, Li Yan-Bing, Zhang Hong-Qi
Abstract excerpt
OBJECTIVE: To investigate the relationship between melanocortin-3 receptor (MC3R) gene polymorphism and tuberculosis (TB) susceptibility in Han population in southern China. METHODS: A total of 341 patients with TB (173 with pulmonary TB and 168 with multifocal TB) and 359 healthy controls were enrolled. Genotyping was performed by PCR and DNA sequencing, and detection of protein was performed by western blot....
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