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Article

The T657C polymorphism on the SYCP3 gene is associated with recurrent pregnancy loss.

Journal of assisted reproduction and genetics - 1 Oct 2014

Sazegari Ali, Kalantar Seyyed Mehdi, Pashaiefar Hossein, Mohtaram Shirin, Honarvar Negar, Feizollahi Zahra, Ghasemi Nasrin

Abstract excerpt

SYCP3 (Sinaptonemal complex protein 3) plays a critical role in pairing and recombination of homologous chromosomes in meiosis 1. It has been shown that lack of this gene leads to infertility in male and weakened fertility in female mice. In a case-control study, we investigated the SYCP3T657C polymorphism in the genome of 100 Iranian women with recurrent pregnancy losses of unknown causes as well as 100 control...

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Identifiers

PMID: 25059562
DOI: 10.1007/s10815-014-0272-6
PMCID: PMC4171419

Genes

SYCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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