Article
Pregnancy after oocyte donation in a patient with NLRP7 gene mutations and recurrent molar hydatidiform pregnancies.
Journal of assisted reproduction and genetics - 1 Sept 2020
Cozette Claire, Scheffler Florence, Lombart Melyne, Massardier Jerome, Bolze Pierre-Adrien, Hajri Touria, Golfier Francois, Touitou Isabelle, Rittore Cecile, Gondry Jean, Merviel Philippe, Benkhalifa Moncef, Cabry Rosalie
Abstract excerpt
Molar pregnancies are benign trophoblastic diseases associated with a risk of malignant transformation. If aetiology remains mostly unknown, the risk of recurrent molar pregnancy is around 1.5% after one molar pregnancy and around 25% after 2 molar pregnancies. In the later situation, genetic mutations have been described, increasing hugely this risk. In case of mutations, probability to obtain a normal pregnancy...
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