Article
Mutation analysis of three genes in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages.
Reproductive biomedicine online - 1 Jan 2011
Stouffs K, Vandermaelen D, Tournaye H, Liebaers I, Lissens W
Abstract excerpt
The primary aim of this study was to gain more insight into maturation arrest of spermatogenesis (MA) and its relationship with mutations in genes essential for meiosis. The study also investigated the possibility that mutations in human meiosis genes cause a milder phenotype and that, in such cases, meiosis could potentially be completed with the production of mature germ cells having an abnormal chromosomal...
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