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Article

Mutations in Genes Coding for Synaptonemal Complex Proteins and Their Impact on Human Fertility.

Cytogenetic and genome research - 1 Jan 2016

Geisinger Adriana, Benavente Ricardo

Abstract excerpt

Human infertility is often classified as idiopathic in both males and females. Meiotic errors may account for at least part of these cases. As the synaptonemal complex (SC, a meiosis-specific protein scaffold) is essential for successful meiosis progression, in this paper, we analyzed the mutations in genes coding for SC components described in infertile patients to assess to what extent alterations in the SC can...

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Identifiers

PMID: 27997882
DOI: 10.1159/000453344

Genes

SYCP3

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Research trail→

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Mutations in Genes Coding for Synaptonemal Complex Proteins and Their Impact on Human Fertility.PMID 27997882Read ↗

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Alterations in synaptonemal complex coding genes and human infertilitySemantic proximity Read ↗

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A rare frameshift mutation inSYCP1is associated with human male infertilitySemantic proximity Read ↗

A rare synaptonemal complex protein 3 gene variant in unexplained female infertility.Semantic proximity Read ↗

Azoospermia in patients heterozygous for a mutation in SYCP3.Semantic proximity Read ↗

Familial primary ovarian insufficiency associated with a <i>SYCE1</i> point mutation: Defective meiosis elucidated in humanized miceSemantic proximity Read ↗

Variations of C14ORF39 and SYCE1 Identified in Idiopathic Premature Ovarian Insufficiency and Nonobstructive Azoospermia.Semantic proximity Read ↗

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