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Article

Characterization of the Mode of Action of a Potent Dengue Virus Capsid Inhibitor

24 Jul 2014

Abstract excerpt

UNLABELLED: Dengue viruses (DV) represent a significant global health burden, with up to 400 million infections every year and around 500,000 infected individuals developing life-threatening disease. In spite of attempts to develop vaccine candidates and antiviral drugs, there is a lack of approved therapeutics for the treatment of DV infection. We have previously reported the identification of ST-148, a...

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PMID: 25056895
DOI: 10.1128/jvi.01745-14

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