Article
In vitro assessment of mouse fetal abdominal aortic vascular function.
American journal of physiology. Regulatory, integrative and comparative physiology - 15 Sept 2014
Renshall Lewis J, Dilworth Mark R, Greenwood Susan L, Sibley Colin P, Wareing Mark
Abstract excerpt
Fetal growth restriction (FGR) affects 3-8% of human pregnancies. Mouse models have provided important etiological data on FGR; they permit the assessment of treatment strategies on the physiological function of both mother and her developing offspring. Our study aimed to 1) develop a method to assess vascular function in fetal mice and 2) as a proof of principle ascertain whether a high dose of sildenafil...
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