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Article

Slmb antagonises the aPKC/Par-6 complex to control oocyte and epithelial polarity.

Development (Cambridge, England) - 1 Aug 2014

Morais-de-Sá Eurico, Mukherjee Avik, Lowe Nick, St Johnston Daniel

Abstract excerpt

The Drosophila anterior-posterior axis is specified when the posterior follicle cells signal to polarise the oocyte, leading to the anterior/lateral localisation of the Par-6/aPKC complex and the posterior recruitment of Par-1, which induces a microtubule reorganisation that localises bicoid and oskar mRNAs. Here we show that oocyte polarity requires Slmb, the substrate specificity subunit of the SCF E3 ubiquitin...

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Source

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Identifiers

PMID: 25053432
DOI: 10.1242/dev.109827
PMCID: PMC4197659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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