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Article

Motility of select ovarian cancer cell lines: Effect of extracellular matrix proteins and the involvement of PAK2

22 Jul 2014

Abstract excerpt

The interaction between tumor cells and extracellular matrix (ECM) proteins influences cell migration and the invasive behavior of cancer cells. In this study, we provide experimental evidence that collagen I and fibronectin affect ovarian cancer cell migration. In vitro wound healing assays and transwell migration assays were used to measure both total wound healing and directionality of individually migrating...

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Identifiers

PMID: 25050916
DOI: 10.3892/ijo.2014.2553

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