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Article

P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910.

International journal of oncology - 1 Oct 2010

Li Liang-Hui, Zheng Min-Hua, Luo Qi, Ye Qing, Feng Bo, Lu Ai-Guo, Wang Ming-Liang, Chen Xue-Hua, Su Li-Ping, Liu Bing-Ya

Abstract excerpt

Pak1 has been reported to be overexpressed in colorectal cancer, but the role of Pak1 in colorectal cancer remains unclear. In this study, Pak1 expression and activity were associated with aggressive behavior of colorectal cancer. Overexpression of Pak1 increased colorectal cancer cell motility a...

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PMID: 20811717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20811717-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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