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Article

Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype.

International journal of cancer - 1 May 2009

Sodek Katharine L, Ringuette Maurice J, Brown Theodore J

Abstract excerpt

Ovarian cancer cells are present in malignant ascites both as individual cells and as multicellular spheroid aggregates. Although spheroid formation affords protection of cancer cells against some chemotherapeutic agents, it has not been established whether a relationship exists between invasive behavior and predisposition to spheroid formation. Aspects of spheroid formation, including cell-matrix adhesion,...

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Source

Identifiers

PMID: 19132753
DOI: 10.1002/ijc.24188

Genes

CCN2
TGM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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