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Article

Integrated stability and activity control of the Drosophila Rbf1 retinoblastoma protein.

The Journal of biological chemistry - 5 Sept 2014

Zhang Liang, Wei Yiliang, Pushel Irina, Heinze Karolin, Elenbaas Jared, Henry R William, Arnosti David N

Abstract excerpt

The retinoblastoma (RB) family transcriptional corepressors regulate diverse cellular events including cell cycle, senescence, and differentiation. The activity and stability of these proteins are mediated by post-translational modifications; however, we lack a general understanding of how distinct modifications coordinately impact both of these properties. Previously, we showed that protein turnover and activity...

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Identifiers

PMID: 25049232
DOI: 10.1074/jbc.M114.586818
PMCID: PMC4155655

Genes

RBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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