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Article

Targeting HER2 in the treatment of non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Mar 2015

Mar Nataliya, Vredenburgh James J, Wasser Jeffrey S

Abstract excerpt

Oncogenic driver mutations have emerged as major treatment targets for molecular therapies in a variety of cancers. HER2 positivity has been well-studied in breast cancer, but its importance is still being explored in non-small cell lung cancer (NSCLC). Laboratory methods for assessment of HER2 positivity in NSCLC include immunohistochemistry (IHC) for protein overexpression, fluorescent in situ hybridization...

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Identifiers

PMID: 25601485
DOI: 10.1016/j.lungcan.2014.12.018

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