Article
Dual HER2 Blockade in Non-Small Cell Lung Cancer Harboring a HER2 Mutation.
Connecticut medicine - 1 Oct 2015
Mar Nataliya, Vredenburgh James J
Abstract excerpt
Identification of targetable oncogenic mutations in non-small cell lung cancer (NSCLC) has been a major advance in cancer treatment. Laboratory techniques to assess human epidermal growth factor receptor 2 (HER2) positivity in NSCLC include immunohistochemistry (IHC) for protein overexpression, fluorescent in situ hybridization (FISH) for gene amplification, and next generation sequencing (NGS) for HER2 gene...
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