Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases.

Clinical and experimental immunology - 1 Nov 2014

Inoue N, Watanabe M, Ishido N, Katsumata Y, Kagawa T, Hidaka Y, Iwatani Y

Abstract excerpt

Vitamin D is a multi-functional immune regulator, and a low serum concentration of vitamin D promotes autoimmune inflammation. In this study, we evaluate the association between the prognosis of autoimmune thyroid disease (AITD) and the functional polymorphisms of genes that regulate vitamin D metabolism. For 139 Graves' disease (GD) patients, 116 Hashimoto's disease (HD) patients and 76 control subjects, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Cholestanetriol 26-Monooxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P450 Family 2

Share to Graves Disease

Share to Hashimoto Disease

Share to Receptors, Calcitriol

Share to Thyroiditis, Autoimmune

Share to Vitamin D-Binding Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 25046415
DOI: 10.1111/cei.12420
PMCID: PMC4233376

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases.PMID 25046415Read ↗

Genetic susceptibility to autoimmune thyroid diseases in a Chinese Han population: Role of vitamin D receptor gene polymorphisms.Semantic proximity Read ↗

Association of Vitamin D Pathway Gene CYP27B1 and CYP2R1 Polymorphisms with Autoimmune Endocrine Disorders: A Meta-Analysis.Semantic proximity Read ↗

The VDR gene confers a genetic predisposition to Graves' disease and Graves' ophthalmopathy in the Southwest Chinese Han population.Semantic proximity Read ↗

Functional Polymorphisms of the Type 1 and Type 2 Iodothyronine Deiodinase Genes in Autoimmune Thyroid Diseases.Semantic proximity Read ↗

THE STUDY OF VDR FOKI RS2228570 SNP IN AUTOIMMUNE THYROIDITIS.Semantic proximity Read ↗

Polymorphisms in the vitamin D receptor gene and risk of autoimmune thyroid diseases: a meta-analysis.Semantic proximity Read ↗

Vitamin D receptor (ApaI/BsmI) polymorphisms, human leukocyte antigen-DQB2/DRB3 sub-alleles, and endoplasmic reticulum stress: unravelling their interplay in the pathogenesis of Graves' disease in a tertiary care centre.Semantic proximity Read ↗

HLA-DRA Gene Polymorphisms Are Associated with Graves' Disease as an Autoimmune Thyroid Disease.Semantic proximity Read ↗

Vitamin D receptor (VDR) gene polymorphisms and Graves' disease: a meta-analysis.Semantic proximity Read ↗

Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies.Semantic proximity Read ↗

Association between vitamin-D receptor gene FokI polymorphism and Graves' disease among Taiwanese Chinese.Semantic proximity Read ↗

Polymorphisms and expression of toll-like receptors in autoimmune thyroid diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.