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Article

The VDR gene confers a genetic predisposition to Graves' disease and Graves' ophthalmopathy in the Southwest Chinese Han population.

Gene - 15 Aug 2021

Zhou Fangyu, Liang Zhongzhi, Wang Xin, Tan Guiqin, Wei Wenwen, Zheng Guangbing, Ma Xiaomin, Tian Dan, Li Hua, Yu Hongsong

Abstract excerpt

OBJECTIVE: Graves' disease (GD) is a common autoimmune disease manifesting with diffuse symmetric thyroid gland enlargement, pretibial myxedema, and Graves' ophthalmopathy (GO). Recently, the vitamin D receptor (VDR) gene has been linked to various autoimmune diseases. This study aimed to investigate the association of VDR gene polymorphisms with susceptibility to GD and GO in the Southwest Chinese Han...

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Identifiers

PMID: 34077777
DOI: 10.1016/j.gene.2021.145750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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