Article
Transcriptional regulation ofATG9by the Pho23-Rpd3 complex modulates the frequency of autophagosome formation
7 Jul 2014
Abstract excerpt
Studies of the physiological and pathological roles of autophagy have revealed that too little or too much autophagy can be detrimental, and therefore autophagy activity needs to be tightly regulated. Altered transcription of autophagy-related (ATG) genes has been reported in many diseases, and ATG genes can be the most direct targets for the treatment of autophagy-associated diseases. Thus, it is important to...
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