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A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy

2 Nov 2015

Abstract excerpt

Autophagy is a pathway mediating vacuolar degradation and recycling of proteins and organelles, which plays crucial roles in cellular physiology. To ensure its proper cytoprotective function, the induction and amplitude of autophagy are tightly regulated, and defects in its regulation are associated with various diseases. Transcriptional control of autophagy is a critical aspect of autophagy regulation, which...

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PMID: 26649943
DOI: 10.1080/15548627.2015.1099796

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