Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional regulation of autophagy, cell wall stress response and pathogenicity by Pho23 in C. albicans

24 Sept 2022

Abstract excerpt

The modification of chromatin by histone deacetylases (HDACs) has critical roles in transcriptional regulation. In this study, we identified the Rpd3 HDAC complex component Pho23 in Candida albicans and explored its role in the transcriptional regulation of physiological processes. PHO23 deletion increased autophagic activity and upregulated the transcription of ATG genes. Moreover, the deletion of PHO23 severely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Nematode management and characterization studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36152022
DOI: 10.1111/febs.16636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional regulation of autophagy, cell wall stress response and pathogenicity by Pho23 in C. albicansPMID 36152022Read ↗

Roles of P-body factors in <i>Candida albicans</i> filamentation and stress responseSemantic proximity Read ↗

Roles of P-body factors in Candida albicans filamentation and stress responseSemantic proximity Read ↗

Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysisSemantic proximity Read ↗

Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans.Semantic proximity Read ↗

Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae.Semantic proximity Read ↗

The two‐component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis‐induced ROS accumulationSemantic proximity Read ↗

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling.Semantic proximity Read ↗

Systematic Identification and Characterization of Five Transcription Factors Mediating the Oxidative Stress Response in Candida AlbicansSemantic proximity Read ↗

Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosisSemantic proximity Read ↗

The SAGA and NuA4 component Tra1 regulates <i>Candida albicans</i> drug resistance and pathogenesisSemantic proximity Read ↗

The fungal-specific Hda2 and Hda3 proteins regulate morphological switches in the human fungal pathogen <i>Candida albicans</i>Semantic proximity Read ↗

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.